Annotation Detail

Information
Associated Genes
CHRNA5
Associated Variants
CHRNA5 MUTATION
CHRNA5 MUTATION
Associated Disease
Nasopharyngeal carcinoma
Source Database
DisGeNET
Description
We found that individuals with CHRNA5 rs3841324 combined variant genotypes (ins/del+del/del) had a >1.5-fold elevated risk for NPC than those with the ins/ins genotype (adjusted OR = 1.52; 95% CI, 1.16-2.00), especially among ever smokers (adjusted OR = 2.07; 95% CI, 1.23-3.48).
Pubmed
25329654
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2014
Drugs