Annotation Detail

Information
Associated Genes
IKZF1
Associated Variants
GATA3 c.779-1748C>A ( ENST00000346208.4, ENST00000379328.9 )
GATA3 c.779-1748C>A ( ENST00000346208.4, ENST00000379328.9 )
Associated Disease
Leukemia, Lymphocytic, Acute, L1
Source Database
DisGeNET
Description
The rs3824662 risk allele was associated with somatic lesions underlying Ph-like ALL (CRLF2 rearrangement, JAK gene mutation and IKZF1 deletion) and with variation in GATA3 expression.
Pubmed
24141364
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.125428837441606
Year of publication
2013
Drugs