Annotation Detail

Information
Associated Genes
TFRC
Associated Variants
TFRC p.Gly142Ser (p.G142S) ( ENST00000360110.9, ENST00000392396.7, ENST00000420415.5, ENST00000698280.1, ENST00000698283.1, ENST00000698285.1, ENST00000698286.1, ENST00000698290.1, ENST00000698291.1, ENST00000698295.1 )
TFRC p.Gly142Ser (p.G142S) ( ENST00000360110.9, ENST00000392396.7, ENST00000420415.5, ENST00000698280.1, ENST00000698283.1, ENST00000698285.1, ENST00000698286.1, ENST00000698290.1, ENST00000698291.1, ENST00000698295.1 )
Associated Disease
adenoma
Source Database
DisGeNET
Description
In the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, 679 persons with advanced distal adenoma and 697 control persons were genotyped for the two major HFE mutations (C282Y and H63D), one HFE polymorphism (IVS2+4), and one polymorphism (G142S) in the transferrin receptor gene (TFRC).
Pubmed
15668490
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2005
Drugs