Annotation Detail

Information
Associated Genes
LOC102724560
Associated Variants
LOC102724560 MUTATION
LOC102724560 MUTATION
Associated Disease
Neurodegenerative Disorders
Source Database
DisGeNET
Description
A significant reduction in sulphide levels and CBS mRNA expression was observed in the hippocampus of mouse models of lipopolysaccharide-induced neuroinflammation-related diseases, suggesting that decreased levels of endogenous H2S might be involved in the pathogenesis of neuroinflammation-related neurodegenerative diseases.
Pubmed
24874797
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs