Annotation Detail
Information
- Associated Genes
- ABCA1
- Associated Variants
-
ABCA1 MUTATION
ABCA1 MUTATION - Associated Disease
- Neurodegenerative Disorders
- Source Database
- DisGeNET
- Description
- ABCA1 is transcriptionally regulated by Liver X Receptors (LXR) and Retinoic X Receptors (RXR) which provides a starting point for drug discovery and development of synthetic LXR and RXR agonists for treatment of metabolic and neurodegenerative disorders.
- Pubmed
- 24844148
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs