Annotation Detail

Information
Associated Genes
ABCB1
Associated Variants
ABCB1 c.117+4196T>C ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
ABCB1 c.117+4196T>C ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
Associated Disease
ulcerative colitis
Source Database
DisGeNET
Description
In patients with extensive UC a significantly different distribution of genotypes of the MDR1 G/A change located in intron 3 (rs3789243) was observed between carriers/noncarriers of the -25385T risk allele (P = 0.005).
Pubmed
17828778
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0540515725438168
Year of publication
2007
Drugs