Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Asp631Asn (p.D631N) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Asp631Tyr (p.D631Y) ( ENST00000615310.5, ENST00000713926.1, ENST00000355710.8, ENST00000340058.6 )
RET p.Asp631Asn (p.D631N) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Asp631Tyr (p.D631Y) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
pheochromocytoma
Source Database
DisGeNET
Description
Patients with RET D631Y mutations most commonly present with pheochromocytoma and not medullary thyroid carcinoma.
Pubmed
22274720
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.604771992525671
Year of publication
2012
Drugs