Annotation Detail

Information
Associated Genes
JAK3
Associated Variants
JAK3 MUTATION
JAK3 MUTATION
Associated Disease
combined immunodeficiency
Source Database
DisGeNET
Description
We here present the first case of revertant mosaicism in JAK3 deficiency, manifesting as combined immunodeficiency evolving into predominant CD4+ lymphopenia.
Pubmed
25205547
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs