Annotation Detail
Information
- Associated Genes
- TLR3
- Associated Variants
-
TLR3 p.Phe459Leu (p.F459L)
(
ENST00000296795.8,
ENST00000504367.1,
ENST00000508051.2,
ENST00000512264.1,
ENST00000698351.1,
ENST00000698354.1 )
TLR3 p.Phe459= (p.F459=) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 )
TLR3 p.Phe459Leu (p.F459L) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 )
TLR3 p.Phe459= (p.F459=) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 ) - Associated Disease
- liver cirrhosis
- Source Database
- DisGeNET
- Description
- Association analysis showed that the TT genotype of TLR3 rs3775290 was associated with a decreased risk for CHB, HBV-related LC, and HCC (OR=0.52, 95% CI: 0.27-0.99, P=0.048; OR=0.32, 95% CI: 0.14-0.76, P=0.010; OR=0.49, 95% CI: 0.26-0.92, P=0.027).
- Pubmed
- 26024592
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2015
Drugs