Annotation Detail

Information
Associated Genes
TLR3
Associated Variants
TLR3 p.Phe459Leu (p.F459L) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 )
TLR3 p.Phe459= (p.F459=) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 )
TLR3 p.Phe459Leu (p.F459L) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 )
TLR3 p.Phe459= (p.F459=) ( ENST00000296795.8, ENST00000504367.1, ENST00000508051.2, ENST00000512264.1, ENST00000698351.1, ENST00000698354.1 )
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
The results indicated that genetic variant in TLR3 gene rs3775290 polymorphisms may be a protective factor for CHB, HBV-related LC, and HCC in the Chinese population.
Pubmed
26024592
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0048958852191096
Year of publication
2015
Drugs