Annotation Detail

Information
Associated Genes
HBB
Associated Variants
HBB MUTATION
HBB MUTATION
Associated Disease
Beta thalassemia intermedia
Source Database
DisGeNET
Description
The proband, who showed the phenotype of β-thalassemia intermedia (β-TI), was found to be a compound heterozygote for the novel mutation -25 (G>T) (HBB: c.-75G>T) and a codon 17 (HBB: c.52A>T) mutation.
Pubmed
25657036
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,CLINVAR,ORPHANET
DisGENET score for the Gene Disease association
0.244071628081205
Drugs