Annotation Detail

Information
Associated Genes
HBB
Associated Variants
HBB MUTATION
HBB MUTATION
Associated Disease
Alpha thalassemia-2 trait
Source Database
DisGeNET
Description
In addition, co-inheritance of α-thalassemia 2 trait in β-thalassemia/Hb E subjects was associated with milder outcome compared with those with the same β-thalassemia genotypes, confirming the notion of the beneficial effect of a more balanced α:β-globin chain ratio.
Pubmed
25361929
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs