Annotation Detail

Information
Associated Genes
MEFV
Associated Variants
MEFV p.Glu148Gln (p.E148Q) ( ENST00000541159.5, ENST00000339854.8, ENST00000536379.5, ENST00000219596.6 )
MEFV p.Glu148Gln (p.E148Q) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
Associated Disease
familial Mediterranean fever
Source Database
DisGeNET
Description
We identified 1 homozygous (E148Q/E148Q), 1 compound heterozygous (M694V/E148Q) and 5 heterozygous MEFV gene mutations; none had their own and/or family history compatible with familial Mediterranean fever.
Pubmed
20437121
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.752692202909606
Year of publication
2010
Drugs