Annotation Detail

Information
Associated Genes
MEFV
Associated Variants
MEFV p.Glu148Gln (p.E148Q) ( ENST00000541159.5, ENST00000339854.8, ENST00000536379.5, ENST00000219596.6 )
MEFV p.Glu148Gln (p.E148Q) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
Associated Disease
familial Mediterranean fever
Source Database
DisGeNET
Description
The role of the E148Q pyrin mutation in the FMF phenotype remains inconclusive, and some authors even view it as a disease-insignificant polymorphism.
Pubmed
21598804
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.752692202909606
Year of publication
2011
Drugs