Annotation Detail

Information
Associated Genes
BCR
Associated Variants
BCR MUTATION
BCR MUTATION
Associated Disease
lupus erythematosus
Source Database
DisGeNET
Description
We have shown previously that AM14 RF B cells break tolerance in the TC mouse model of lupus through the dual engagement of the AM14 BCR and TLR9.
Pubmed
25957308
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs