Annotation Detail
Information
- Associated Genes
- ESR1
- Associated Variants
-
CCDC170 c.*68A>C
(
ENST00000239374.8 )
rs9383938
CCDC170 c.*68A>C ( ENST00000239374.8 )
rs9383938 - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- We also identified two variants (rs3734805 and rs9383938) mapping to 6q25.1 estrogen receptor 1 (ESR1), which were associated with breast cancer in subjects of northern European ancestry (rs3734805: OR = 1.19, 95% CI = 1.11 to 1.27, P = 1.35 × 10(-7); rs9383938: OR = 1.18, 95% CI = 1.11 to 1.26, P = 1.41 × 10(-7)).
- Pubmed
- 21263130
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.24
- Year of publication
- 2011
Drugs