Annotation Detail
Information
- Associated Genes
- BHMT
- Associated Variants
-
BHMT p.Arg239Gln (p.R239Q)
(
ENST00000274353.10,
ENST00000524080.1 )
BHMT p.Arg239Gln (p.R239Q) ( ENST00000274353.10, ENST00000524080.1 ) - Associated Disease
- Adenoma of large intestine
- Source Database
- DisGeNET
- Description
- We observed significant evidence for departure from multiplicative interaction for the betaine-homocysteine methyltransferase (BHMT) Arg239Gln with dietary methyl status (based on intake of dietary folate, methionine and alcohol intake) in relation to colorectal adenoma; no such interaction was observed for the other 23 SNPs.
- Pubmed
- 17389618
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2007
Drugs