Annotation Detail

Information
Associated Genes
ABCA1
Associated Variants
ABCA1 MUTATION
ABCA1 MUTATION
Associated Disease
Non-alcoholic Fatty Liver Disease
Source Database
DisGeNET
Description
miR-101 promotes intracellular cholesterol retention under inflammatory conditions through suppressing ABCA1 expression and suggests that the miR-101-ABCA1 axis may play an intermediary role in the development of NAFLD and vascular atherosclerosis.
Pubmed
26033364
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs