Annotation Detail

Information
Associated Genes
PIK3R1
Associated Variants
PIK3R1 MUTATION
PIK3R1 MUTATION
PIK3R1 p.Met326Ile (p.M326I) ( ENST00000336483.10, ENST00000521381.6, ENST00000522084.6, ENST00000320694.13, ENST00000517643.2, ENST00000521657.6, ENST00000697457.1, ENST00000697458.1, ENST00000697460.1, ENST00000697461.1, ENST00000697462.1, ENST00000697465.1, ENST00000697466.1 )
PIK3R1 p.Met326Ile (p.M326I) ( ENST00000697460.1, ENST00000697461.1, ENST00000697462.1, ENST00000320694.13, ENST00000336483.10, ENST00000517643.2, ENST00000521381.6, ENST00000521657.6, ENST00000522084.6, ENST00000697457.1, ENST00000697458.1, ENST00000697465.1, ENST00000697466.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
Met326Ile aminoacid polymorphism in the human p85 alpha gene has no major impact on early insulin signaling in type 2 diabetes.
Pubmed
15523593
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0887297471682879
Year of publication
2004
Drugs