Annotation Detail

Information
Associated Genes
SMPD1
Associated Variants
SMPD1 p.Arg602His (p.R602H) ( ENST00000527275.5, ENST00000342245.9 )
SMPD1 p.Arg602His (p.R602H) ( ENST00000342245.9, ENST00000527275.5 )
Associated Disease
Niemann-Pick Diseases
Source Database
DisGeNET
Description
For this purpose, we have used cultured Niemann-Pick disease (NPD) lymphoid cells with a defined mutation (R600H) in the aSMase protein.
Pubmed
9516458
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.266098145806366
Year of publication
1998
Drugs