Annotation Detail
Information
- Associated Genes
- MTHFR
- Associated Variants
-
TXNRD1 c.304+7698C>T
(
ENST00000525566.6 )
TXNRD1 c.304+7698C>T ( ENST00000525566.6 ) - Associated Disease
- Leukemia, Lymphocytic, Acute, L1
- Source Database
- DisGeNET
- Description
- Further, at least two studies now show that the inactivating NAD(P)H:quinone acceptor oxidoreductase (NQO1) C609T polymorphism is positively associated with leukemias arising in the first 1-2 years of life and polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene have been associated with adult and childhood ALL.
- Pubmed
- 15967214
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0305323114581486
- Year of publication
- 2005
Drugs