Annotation Detail

Information
Associated Genes
TARDBP
Associated Variants
TARDBP p.Ala382Thr (p.A382T) ( ENST00000240185.8, ENST00000700088.1, ENST00000621790.4, ENST00000315091.7, ENST00000616545.4, ENST00000639083.1, ENST00000649624.1, ENST00000629725.2 )
TARDBP p.Ala382Pro (p.A382P) ( ENST00000639083.1, ENST00000616545.4, ENST00000315091.7, ENST00000629725.2, ENST00000649624.1, ENST00000240185.8, ENST00000700088.1, ENST00000621790.4 )
TARDBP p.Ala382Thr (p.A382T) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
TARDBP p.Ala382Pro (p.A382P) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
Associated Disease
amyotrophic lateral sclerosis
Source Database
DisGeNET
Description
The TARDBP p.A382T missense mutation accounts for approximately one-third of all ALS cases in this island population.
Pubmed
21220647
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.379801509465824
Year of publication
2011
Drugs