Annotation Detail

Information
Associated Genes
TARDBP
Associated Variants
TARDBP p.Ala382Thr (p.A382T) ( ENST00000240185.8, ENST00000700088.1, ENST00000621790.4, ENST00000315091.7, ENST00000616545.4, ENST00000639083.1, ENST00000649624.1, ENST00000629725.2 )
TARDBP p.Ala382Pro (p.A382P) ( ENST00000639083.1, ENST00000616545.4, ENST00000315091.7, ENST00000629725.2, ENST00000649624.1, ENST00000240185.8, ENST00000700088.1, ENST00000621790.4 )
TARDBP p.Ala382Thr (p.A382T) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
TARDBP p.Ala382Pro (p.A382P) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
Associated Disease
dementia
Source Database
DisGeNET
Description
Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations.
Pubmed
20697052
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.017064619157595
Year of publication
2010
Drugs