Annotation Detail

Information
Associated Genes
GJB2
Associated Variants
GJB2 p.Met34Arg (p.M34R) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Met34Thr (p.M34T) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Met34Arg (p.M34R) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Met34Thr (p.M34T) ( ENST00000382844.2, ENST00000382848.5 )
Associated Disease
Hearing Loss, Mixed Conductive-Sensorineural
Source Database
DisGeNET
Description
These data support the hypothesis of a functional role for M34T as a dominant allele and represent a further step towards a complete understanding of the role of GJB2 in causing hearing loss.
Pubmed
12176036
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0646031655551122
Year of publication
2002
Drugs