Annotation Detail

Information
Associated Genes
EPHB2
Associated Variants
EPHB2 MUTATION
EPHB2 MUTATION
Associated Disease
Malignant neoplasm of prostate
Source Database
DisGeNET
Description
Finally, the results demonstrated that AQP3 upregulated matrix metalloproteinase‑3 (MMP‑3) expression and secretion in prostate cancer cells via activation of the ERK pathway.
Pubmed
25515250
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD,UNIPROT
DisGENET score for the Gene Disease association
0.131867497501413
Drugs