Annotation Detail
Information
- Associated Genes
- TLR9
- Associated Variants
-
TLR9 p.Pro545= (p.P545=)
(
ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 ) - Associated Disease
- HIV Infections
- Source Database
- DisGeNET
- Description
- Infants with the TLR9 1635A (rs352140) variant were more likely to acquire HIV-1 by 1 month [hazard ratio = 1.81, 95% confidence interval (CI) = 1.05-3.14, P = 0.033] and by 12 months (hazard ratio = 1.62, CI = 1.01-2.60, P = 0.044) in dominant models adjusted for maternal plasma HIV-1 RNA level and genetic ancestry.
- Pubmed
- 24037211
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0109012821449303
- Year of publication
- 2014
Drugs