Annotation Detail

Information
Associated Genes
TLR9
Associated Variants
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 c.4-44A>G ( ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 c.4-44A>G ( ENST00000360658.3 )
Associated Disease
Acute GVH disease
Source Database
DisGeNET
Description
We found that two tagSNPs in the TLR9 gene in the donor side, +1174 A/G (rs352139) and +1635 C/T (rs352140), influenced the risk of acute GVHD (aGVHD) and CMV reactivation.
Pubmed
24121213
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2013
Drugs