Annotation Detail

Information
Associated Genes
MLH1
Associated Variants
MLH1 MUTATION
MLH1 MUTATION
Associated Disease
Malignant neoplasm of prostate
Source Database
DisGeNET
Description
This study provides statistical evidence that MMR deficiency is correlated with hypermethylation of hMLH1 promoter and upregulation of hsa-miR-155, hsa-miR-141 and hsa-miR-21 in prostate cancer.
Pubmed
25938433
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0121825466352112
Drugs