Annotation Detail
Information
- Associated Genes
- PLEKHA1
- Associated Variants
-
ARMS2 p.Ala69Ser (p.A69S)
(
ENST00000528446.1 )
ARMS2 p.Ala69Ser (p.A69S) ( ENST00000528446.1 ) - Associated Disease
- age related macular degeneration
- Source Database
- DisGeNET
- Description
- We demonstrate, by evaluating 45 tag SNPs spanning HTRA1, PLEKHA1, and predicted gene LOC387715/ARMS2, that rs10490924 SNP alone, or a variant in strong linkage disequilibrium, can explain the bulk of association between the 10q26 chromosomal region and AMD.
- Pubmed
- 17884985
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0222794346855647
- Year of publication
- 2007
Drugs