Annotation Detail

Information
Associated Genes
LRRK2
Associated Variants
LRRK2 p.Gly2019Ser (p.G2019S) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Gly2019Ser (p.G2019S) ( ENST00000298910.12, ENST00000680790.1 )
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
Investigation of the leucine-rich repeat kinase 2 (LRRK2) gene in late-onset Alzheimer's disease (AD) patients to screen for the G2019S mutation, which is common in Parkinson's cases.
Pubmed
17846883
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0209222253251632
Year of publication
2007
Drugs