Annotation Detail

Information
Associated Genes
TYK2
Associated Variants
TYK2 MUTATION
TYK2 MUTATION
TYK2 p.Pro1104Ala (p.P1104A) ( ENST00000524462.5, ENST00000525621.6, ENST00000525976.6, ENST00000531836.6, ENST00000699360.1, ENST00000699365.1 )
TYK2 p.Pro1104Ala (p.P1104A) ( ENST00000524462.5, ENST00000525621.6, ENST00000525976.6, ENST00000531836.6, ENST00000699360.1, ENST00000699365.1 )
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
In this study, we characterized two rare Tyk2 variants, I684S and P1104A, which have been associated with susceptibility to autoimmune disease.
Pubmed
23359498
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00408155960286869
Year of publication
2013
Drugs