Annotation Detail

Information
Associated Genes
LRRK2
Associated Variants
LRRK2 p.Pro755Leu (p.P755L) ( ENST00000298910.12, ENST00000343742.6, ENST00000680790.1 )
LRRK2 p.Pro755Leu (p.P755L) ( ENST00000298910.12, ENST00000343742.6, ENST00000680790.1 )
Associated Disease
Parkinson disease
Source Database
DisGeNET
Description
To evaluate the frequency of the LRRK2 P755L variant in North American Caucasian patients with PD, we screened 426 PD patients and 37 additional patients with the combination of PD and essential tremor (ET) from our Parkinson Disease Center and Movement Clinic at Baylor College of Medicine.
Pubmed
17482357
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.4358303271146
Year of publication
2007
Drugs