Annotation Detail

Information
Associated Genes
JAK3
Associated Variants
JAK3 MUTATION
JAK3 MUTATION
Associated Disease
Disseminated Malignant Neoplasm
Source Database
DisGeNET
Description
In addition, H69 cells with v.NICD were xenotransplanted into immune-compromised Rag2(-/-) Jak3(-/-) mice, for analysis of ex vivo tumor epithelial mesenchymal transition (EMT) phenotype and for detection of metastatic cancer cells in the lung tissues.
Pubmed
25456735
Section of the abstract supporting the evidence
MATERIALS AND METHODS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs