Annotation Detail

Information
Associated Genes
ARMS2
Associated Variants
ARMS2 p.Ala69Ser (p.A69S) ( ENST00000528446.1 )
ARMS2 p.Ala69Ser (p.A69S) ( ENST00000528446.1 )
Associated Disease
age related macular degeneration
Source Database
DisGeNET
Description
[The significant association is retained following multivariate analysis with adjustment for age, smoking status, Complement Factor H (CFH), Age-Related Maculopathy Susceptibility 2 (ARMS2), Complement Component 2 (CC2), and Complement Factor B (CFB; OR=1.45; CI: 1.10-1.91; p=0.009).]
Pubmed
20157618
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.403743137904031
Year of publication
2010
Drugs