Annotation Detail

Information
Associated Genes
MUTYH
Associated Variants
MUTYH p.Arg238Trp (p.R238W), ENSG00000288208 p.Arg409Trp (p.R409W) ( ENST00000456914.7, ENST00000354383.10, ENST00000672314.2, ENST00000483127.2, ENST00000372115.7, ENST00000529984.5, ENST00000355498.6, ENST00000528013.6, ENST00000412971.6, ENST00000372104.5, ENST00000713751.1, ENST00000488731.6, ENST00000672818.3, ENST00000531105.5, ENST00000529892.6, ENST00000372098.7, ENST00000448481.5, ENST00000710952.2, ENST00000372110.7, ENST00000713750.1 )
MUTYH p.Arg238Trp (p.R238W), ENSG00000288208 p.Arg409Trp (p.R409W) ( ENST00000354383.10, ENST00000355498.6, ENST00000372098.7, ENST00000372104.5, ENST00000372110.7, ENST00000372115.7, ENST00000412971.6, ENST00000448481.5, ENST00000456914.7, ENST00000483127.2, ENST00000488731.6, ENST00000528013.6, ENST00000529892.6, ENST00000529984.5, ENST00000531105.5, ENST00000672314.2, ENST00000672818.3, ENST00000710952.2, ENST00000713750.1, ENST00000713751.1 )
Associated Disease
Colorectal Adenomatous Polyposis, Autosomal Recessive
Source Database
DisGeNET
Description
Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas.
Pubmed
15366000
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.48027144187208
Year of publication
2004
Drugs