Annotation Detail

Information
Associated Genes
HBB
Associated Variants
HBB p.Glu27Ter (p.E27*) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HBB p.Glu27Gln (p.E27Q) ( ENST00000485743.1, ENST00000335295.4, ENST00000647020.1 )
HBB p.Glu27Lys (p.E27K) ( ENST00000485743.1, ENST00000335295.4, ENST00000647020.1 )
HBB p.Glu27Ter (p.E27*) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HBB p.Glu27Gln (p.E27Q) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HBB p.Glu27Lys (p.E27K) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
Associated Disease
Hemoglobinopathies
Source Database
DisGeNET
Description
Hemoglobin E (E26K variant of beta-globin gene) causing hemoglobinopathy is commonly observed in parts of Thailand, regardless of the hematologic disadvantage of the homozygotes.
Pubmed
19230568
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.262888331778182
Year of publication
2003
Drugs