Annotation Detail

Information
Associated Genes
OR10A4
Associated Variants
HBB p.Glu7Val (p.E7V) ( ENST00000647020.1, ENST00000485743.1, ENST00000335295.4 )
HBB p.Glu7Gly (p.E7G) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HBB p.Glu7Ala (p.E7A) ( ENST00000485743.1, ENST00000335295.4, ENST00000647020.1 )
HP c.-131C>G ( ENST00000355906.10 )
HP c.-91A>C ( ENST00000355906.10 )
HP c.-91A>G ( ENST00000355906.10 )
HBB p.Glu7Val (p.E7V) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HBB p.Glu7Gly (p.E7G) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HBB p.Glu7Ala (p.E7A) ( ENST00000335295.4, ENST00000485743.1, ENST00000647020.1 )
HP c.-131C>G ( ENST00000355906.10 )
HP c.-91A>C ( ENST00000355906.10 )
HP c.-91A>G ( ENST00000355906.10 )
Associated Disease
Sickle Cell Trait
Source Database
DisGeNET
Description
The objective was to investigate whether haptoglobin (Hp) haplotypes constructed from the functional polymorphism (Hp1/Hp2) plus the functional promoter SNPs -61A-C (rs5471) and -101C-G (rs5470), or sickle cell trait (HbAS, rs334) were associated with risk of active trachoma when stratified by age and sex, in rural Gambian children.
Pubmed
20552021
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2010
Drugs