Annotation Detail
Information
- Associated Genes
- MDM2
- Associated Variants
-
MDM2 MUTATION
MDM2 MUTATION - Associated Disease
- Malignant neoplasm of pancreas
- Source Database
- DisGeNET
- Description
- In combination treatments, PRIMA-1 enhanced the anti-tumor activity of several chemotherapic drugs against pancreatic cancer cells and also exhibited a pronounced synergistic effect in association with the Mdm2 inhibitor Nutlin-3.
- Pubmed
- 24838627
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00271441872080303
Drugs