Annotation Detail
Information
- Associated Genes
- XRCC2
- Associated Variants
-
XRCC2 p.Arg188His (p.R188H)
(
ENST00000359321.2,
ENST00000698506.1 )
XRCC2 p.Arg188His (p.R188H) ( ENST00000359321.2, ENST00000698506.1 ) - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- However, when the population was stratified according to breast feeding (women that breast fed and women that never breast fed) it is observed, in women that never breast fed, that the heterozygous individuals for the XRCC2 (Ex3+442G>A, R188H, rs3218536) polymorphism have a decreased risk for breast cancer [adjusted OR=0.45; 95% CI=0.22-0.92] (P=0.03).
- Pubmed
- 20004634
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00542883744160607
- Year of publication
- 2010
Drugs