Annotation Detail

Information
Associated Genes
XRCC2
Associated Variants
XRCC2 p.Arg188His (p.R188H) ( ENST00000359321.2, ENST00000698506.1 )
XRCC2 p.Arg188His (p.R188H) ( ENST00000359321.2, ENST00000698506.1 )
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
None of these tagging SNPs was associated with breast cancer risk, with the exception of XRCC2 rs3218536, R188H, which showed some evidence of a protective association for the rare allele [per allele odds ratio, 0.89; 95% confidence intervals (95% CI), 0.80-0.99; P trend = 0.03].
Pubmed
19064565
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0362002531634325
Year of publication
2008
Drugs