Annotation Detail
Information
- Associated Genes
- XRCC3
- Associated Variants
-
XRCC2 p.Arg188His (p.R188H)
(
ENST00000359321.2,
ENST00000698506.1 )
XRCC2 c.40-2317C>T ( ENST00000359321.2, ENST00000698506.1 )
XRCC2 p.Arg188His (p.R188H) ( ENST00000359321.2, ENST00000698506.1 )
XRCC2 c.40-2317C>T ( ENST00000359321.2, ENST00000698506.1 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- We prospectively assessed the associations of candidate polymorphisms G31479A (R188H) in XRCC2, A4541G (5'-UTR), A17893G (IVS5-14) and C18067T (T241 M) in XRCC3, and C299T (5'-UTR) and T1977C (D501D) in Ligase IV with breast cancer risk in a nested case-control study within the Nurses' Health Study (incident cases, n=1004; controls, n=1385).
- Pubmed
- 14578164
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0845071080919554
- Year of publication
- 2004
Drugs