Annotation Detail

Information
Associated Genes
ARMS2
Associated Variants
ARMS2 p.Ala69Ser (p.A69S) ( ENST00000528446.1 )
ARMS2 p.Ala69Ser (p.A69S) ( ENST00000528446.1 )
Associated Disease
age related macular degeneration
Source Database
DisGeNET
Description
In this large GWAS meta-analysis and replication analysis, the ARMS2/HTRA1 locus confers increased risk for both advanced AMD subtypes, but imparts greater risk for CNV than for GA.
Pubmed
22705344
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.403743137904031
Year of publication
2012
Drugs