Annotation Detail
Information
- Associated Genes
- IL12B
- Associated Variants
-
IL12B c.*159A>C
(
ENST00000231228.3,
ENST00000696750.1 )
IL12B c.*159A>C ( ENST00000231228.3, ENST00000696750.1 ) - Associated Disease
- Chronic small plaque psoriasis
- Source Database
- DisGeNET
- Description
- Various single-nucleotide polymorphisms (SNP) have been identified in the IL12B gene, such as SNP 3' UTR 1188 A/C (SNP rs3212227), which has been associated with susceptibility to developing plaque psoriasis and with the production of IL-12 and IL-23 in individuals of different ethnic groups.
- Pubmed
- 25447399
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs