Annotation Detail

Information
Associated Genes
IL12B
Associated Variants
IL12B c.*159A>C ( ENST00000231228.3, ENST00000696750.1 )
rs6887695
IL12B c.*159A>C ( ENST00000231228.3, ENST00000696750.1 )
rs6887695
Associated Disease
Psoriasis vulgaris
Source Database
DisGeNET
Description
For both PA and PV, we detected the strongest association with two IL12B single-nucleotide polymorphisms and the corresponding haplotype as reflected by minimal P-values of 10(-7) and highest odds ratios of 1.50 (1.28-1.75) for rs6887695 in PA patients and 1.50 (1.27-1.76) for rs3212227 in the PV cohort, respectively.
Pubmed
18800148
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Year of publication
2009
Drugs