Annotation Detail

Information
Associated Genes
SH2B3
Associated Variants
SH2B3 p.Trp262Arg (p.W262R) ( ENST00000341259.7, ENST00000538307.1 )
SH2B3 p.Trp262Arg (p.W262R) ( ENST00000341259.7, ENST00000538307.1 )
Associated Disease
Diabetes Mellitus, Insulin-Dependent
Source Database
DisGeNET
Description
The carriage of the type 1 diabetes-associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients.
Pubmed
20546165
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.257654991338535
Year of publication
2011
Drugs