Annotation Detail

Information
Associated Genes
CYP1B1
Associated Variants
CYP1B1 MUTATION
CYP1B1 MUTATION
Associated Disease
Irido-corneo-trabecular dysgenesis (disorder)
Source Database
DisGeNET
Description
We report here an 8-year-old patient with 22q11.2 deletion syndrome and bilateral Peters anomaly with congenital glaucoma; in addition, our patient was found to have a single heterozygous mutation in CYP1B1, c.83C > T, p.(Ser28Trp).
Pubmed
24024747
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,ORPHANET
DisGENET score for the Gene Disease association
0.361085767488321
Drugs