Annotation Detail

Information
Associated Genes
APOA5
Associated Variants
APOA5 p.Ser19Leu (p.S19L) ( ENST00000673688.1, ENST00000227665.9, ENST00000542499.5 )
APOA5 p.Ser19Trp (p.S19W) ( ENST00000542499.5, ENST00000227665.9, ENST00000673688.1 )
rs662799
APOA5 p.Ser19Leu (p.S19L) ( ENST00000227665.9, ENST00000542499.5, ENST00000673688.1 )
APOA5 p.Ser19Trp (p.S19W) ( ENST00000227665.9, ENST00000542499.5, ENST00000673688.1 )
rs662799
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
In conclusion, polymorphisms in genes associated to the development of atherogenic dyslipidemia, especially variants in APOA5 gene (rs3135506 and rs662799), can influence the circulating CD4 T-cell levels in chronically HIV-infected patients.
Pubmed
25500319
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00527694770136467
Year of publication
2014
Drugs