Annotation Detail

Information
Associated Genes
CPA4
Associated Variants
CPA4 MUTATION
CPA4 MUTATION
Associated Disease
eosinophilic esophagitis
Source Database
DisGeNET
Description
Bioinformatics analysis revealed largely overlapping transcriptomes between patients with PPI-REE and those with EoE, including the genes for eosinophil chemotaxis (eotaxin 3, CCL26), barrier molecules (desmoglein 1, DSG1), tissue remodeling (periostin, POSTN), and mast cells (carboxypeptidase A, CPA3).
Pubmed
25441638
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs