Annotation Detail
Information
- Associated Genes
- HLA-DPA1
- Associated Variants
-
HLA-DPA1 c.*115T>C
(
ENST00000419277.5,
ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- hepatitis B
- Source Database
- DisGeNET
- Description
- Japanese patients (202) who were hepatitis B e antigen positive at baseline, received LAM as first-line treatment, and consented to HLA-DP genotyping (HLA-DPA1 rs3077 and HLA-DPB1 rs9277535) were categorized into two cohorts, viz., a cohort who achieved virological response without rescue therapy (cohort 1) and those who did so with rescue therapy (cohort 2).
- Pubmed
- 25103089
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.122714418720803
- Year of publication
- 2014
Drugs