Annotation Detail

Information
Associated Genes
HLA-DPA1
Associated Variants
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.364+1567A>G ( ENST00000428835.6, ENST00000416804.2, ENST00000418931.7, ENST00000714454.1 )
rs3128917
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.364+1567A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6, ENST00000714454.1 )
rs3128917
Associated Disease
hepatitis B
Source Database
DisGeNET
Description
We genotyped SNPs rs3077 (near HLA-DPA1) and rs9277378 and rs3128917 (both near HLA-DPB1) in 500 HBV carriers (hepatitis B surface antigen [HBsAg]-positive), 245 non-HBV infected controls (HBsAg- and antibody to hepatitis B core protein [anti-HBc]-negative), and 259 subjects with natural HBV clearance (HBsAg-negative, anti-HBc-positive).
Pubmed
23825586
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.122714418720803
Year of publication
2013
Drugs